Cerenex Pharmaceuticals, Research Triangle Pk, NC. It’s a drug that blocks the action of serotonin, a naturally occurring substance that can lead to nausea and vomiting. Transient visual disturbances, blurred vision, and transient blindness occurred predominantly during rapid IV administration. Slow Heartbeat 14. [Ref], Very common (10% or more): Wound problem (up to 28%), malaise/fatigue (up to 13%), Common (1% to 10%): Shivers, pyrexia/fever, cold sensation, Frequency not reported: Pain, ear disorder[Ref], Very common (10% or more): Diarrhea (up to 16%), constipation (up to 11%), Common (1% to 10%): Xerostomia, nausea, vomiting, localized anal/rectal burning sensation, Frequency not reported: Gastric symptoms, abdominal pain, flatulence[Ref], Localized anal/rectal burning occurred after insertion of the suppository formulation.[Ref]. Oculogyric crisis occurred alone and in combination with other dystonic reactions. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Most side effects of Zofran are mild or moderate, but some may be severe or life-threatening. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. O 0. Decreased Oxygen In The Tissues Or Blood 7. Zofran® May Cause Harmful Interactions With Certain Foods, Drugs, And Medical Conditions There's a lot of controversy surrounding the anti-nausea medication Zofran®, particularly when it's used by pregnant women. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Zofran is a drug with problematic side effects. There are no adequate studies of Zofran in pregnant women to determine its safe and effective use during pregnancy. Studies have linked Zofran to severe side effects, including birth defects, heart defects, cleft palate, and more. Abnormal Heart Electrical Signals 2. Hundreds of women have turned to the legal system to get justice and restitution for unexpected side effects that have changed lives forever. Transient, asymptomatic increases in AST/ALT 2 times the upper limit of normal commonly occurred in patients receiving chemotherapy with cisplatin, and did not appear to be related to dose/duration of treatment. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. At the extreme end, the use of the drug caused fetal death including miscarriage and stillbirth. Zuplenz (ondansetron)." Medically reviewed by Drugs.com. This drug is more popular than comparable drugs. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is also effective for treating gastroenteritis. WebMD does not provide medical advice, diagnosis or treatment. If these effects persist or worsen, notify your doctor promptly. Zofran (ondansetron) comes in many different forms that you don't have to swallow, such as a film that goes on the tongue or a dissolving pill. Common side effects associated with Zofran include headache, drowsiness, constipation and the chills. Available for Android and iOS devices. More common side effects. Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The effects of Zofran were never investigated in clinical trials that included pregnant women, and thus there are no clinical trials targeting pregnant women that would provide us with a way of knowing what side effects it may cause in them or harm it may do to developing babies. It can be given by mouth or by injection into a muscle or into a vein. Zofran (ondansetron) is fast-acting and starts working within 30 minutes. Extrapyramidal Reaction 8. Potential pregnancy side effects of Zofran have been linked to an increased risk of unborn babies developing serious … This drug is more popular than comparable drugs. Some side effects may not be reported. Doctors also prescribe it to pregnant women who have extreme or debilitating morning sickness. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Ondansetron is a common medication that can be used to treat vomiting in dogs and cats. [Ref], Wound problems occurred at the surgical site in patients given this drug for the treatment of postoperative nausea and vomiting. Most patients were receiving concomitant chemotherapy with cisplatin. Unlike some other nausea medicines, the side effects for Zofran (ondansetron… The following article provides more detailed information on the use, side effects, and drawbacks of this drug. "Product Information. Giant Hives 10. We comply with the HONcode standard for trustworthy health information -. Note: This document contains side effect information about ondansetron. 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