What’s the plant origin? Look out for brands that have been independently tested by companies such as ConsumerLab.com, USP, or NSF International. Cat’s claw cream can also be used as a topical treatment of arthritis, rheumatism, and various muscle and joint problems. Provides Arthritis Relief. Cat’s claw appears to have few side effects but presently very little scientific research has been done on the benefits and possible side effects of this herb. Cat’s claw also appears to have positive immune system effects when it comes to herpes. The supplement groups also had an increase in white blood cell proliferation, which is also a huge finding since chemotherapy commonly reduces white blood cell counts and increases infection risk. In vivo studies have shown that water-soluble extracts of cat’s claw (C-Med-100) can enhance DNA repair, mitogenic response and leukocyte recovery after chemotherapy-induced DNA damage. The former is the type often used in supplements in the United States (2). However, after eight weeks, the benefits were not sustained. Cat’s claw is a tropical vine used for centuries as a traditional medicine. (5) I’ve previously written about cat’s claw as one of the best antiviral herbs to boost the immune system and fight infection. Another small study in four men given cat’s claw extract for six weeks noted the same results (4). What Is Cat’s Claw. Researchers found that “pain associated with activity, medical and patient assessment scores were all significantly reduced with benefits occurring within the first week of therapy.” Knee pain at rest or at night and knee circumference were not significantly reduced by cat’s claw during the short trial, but results led researchers to conclude that cat’s claw is an effective treatment for osteoarthritis with no significant side effects. This herb has undergone quite a bit of medical research since the 1970’s. Cats Claw has many phytochemical elements that consist of oxidole alkaloids, quinovic acid glycosides, antioxidants, plant sterols and carboxyl alkyl esters. One of its most popular uses in the United States is for the treatment of various forms of arthritis, and science backs up this usage. Maybe it can help you too. Available information to develop dosage guidelines for cat’s claw is insufficient. Multiples studies have confirmed using cat’s claw to naturally improve both osteoarthritis and rheumatoid arthritis symptoms. Cat’s claw seems to work both by boosting your immune response and calming an overactive immune system (3, 5). Another trial tested a daily mineral supplement alongside 100 mg of cat’s claw extract in people with osteoporosis. The results showed “statistically significant immune enhancement” in the individuals taking the cat’s claw supplements compared to the untreated control group. are clickable links to these studies. In traditional medicine, cat’s claw was used in the treatment of inflammation, dysentery, gastric ulcers, rheumatism, arthritis, wounds, and cancer. There have been several areas of interest in the research related to Cat's Claw, most notably the effects on the immune system and the inflammatory pathways in the human body. Scientists believe that cat’s claw may ease osteoarthritis symptoms due to its anti-inflammatory properties (6, 8). Known to cure arthritis. It has been used for years by the local tribes as a way to boost the immune system, which is why medical professionals have recently been performing studies about cat's claw and the brain. A 2015 study also found that the cat’s claw might be especially beneficial to advanced cancer patients by improving their quality of life and reducing fatigue. Calcium channel blockers also widen and relax the blood vessels themselves, which helps blood flow in a healthy, smooth manner. It’s said to contain over 30 known constituents, including at least 17 alkaloids, along with glycosides, tannins, flavonoids, sterol fractions and other compounds. The suggested dosage for C-Med-100, a patented extract of cat’s claw (Uncaria tomentosa) bark, is 300 milligrams daily. This means that cat’s claw could likely be helpful in warding off heart attacks and strokes by not only decreasing blood pressure and increasing circulation, but by also inhibiting the formation of plaque and blood clots in the arteries, heart and brain. However, diarrhea or loose stools are typically mild and subside with continued use of the herb. Four of the five alkaloids inhibited the proliferation of human leukemia cells in the lab, but the researchers found that cat’s claw pteropodine and uncarine F both were especially impressive. The herpes-fighting ability of cat’s claw is associated with its polyphenols working synergistically with its oxindole alkaloids or quinovic acid glycosides. (9). However, there was no change in either pain at rest or knee swelling (8). Complementary and alternative treatments for osteoarthritis may help you manage symptoms. (17) If you can naturally calm the inflammation, unwanted Crohn’s symptoms should improve greatly. It’s easy to find cat’s claw supplements at your nearest health store or online. Inflammation. (8), A 2006 study wanted to evaluated the ability of a water-soluble cat’s claw extract to enhance DNA repair in human skin. These can include herbs and supplements like turmeric and…, Lyme disease natural treatments: Do they exist? Cat’s claw contains several powerful compounds — such as phenolic acids, alkaloids, and flavonoids — that may promote health (14, 15). It is also used to manage disease and for the treatment of wounds. Once in Pozuzo, Brell used cat’s claw to treat his own rheumatic pain. (11). Several herbs may help lower high blood pressure. In vivo studies have shown that water-soluble extracts of cat’s claw … Test tube studies also demonstrate that cat’s claw can stimulate the immune system, dilate blood vessels, act as a diuretic and relax smooth muscles (like the intestines). It’s important to know that this plant, Senegalia greggii, has no known health benefits and contains potentially poisonous elements. However, WHO says that an average daily dose is 20–350 mg of dried stem bark for extracts or 300–500 mg for capsules, taken in 2–3 separate doses throughout the day (21). Cat's claw has had a history of folkloric use in South America for wound healing and for treating arthritis, gastric ulcers, intestinal disorders, and some skin disorders and tumors. It is generally advised that the following groups of people should avoid or limit cat’s claw: The lack of safety evidence means that you should always use cat’s claw with caution. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Herbs and Supplements to Treat Crohn’s Disease, 10 Herbs That May Help Lower High Blood Pressure. Two species of cat’s claw are commonly used in North America and Europe. Keep in mind that more research is needed on cat’s claw and osteoarthritis (11). Cat’s claw has also been shown to inhibit platelet aggregation and blood clot formation. Cat's claw has been used in alternative medicine as a possibly effective aid in treating arthritis. These health-promoting attributes may make cat’s claw helpful as a natural treatment for arthritis, allergies, asthma, diabetes, chronic fatigue syndrome, cancer, viral infections, ulcers, hemorrhoids and more. It is found mainly in the Amazon rainforest and in other tropical areas of South and Central America. Cat’s claw, specifically Uncaria tomentosa, is believed to be able to help fight the inflammation associated with Crohn’s. Dr. Josh Axe is on a mission to provide you and your family with the highest quality nutrition tips and healthy recipes in the world...Sign up to get VIP access to his eBooks and valuable weekly health tips for FREE! They found that this supplementation significantly elevated subjects’ infection-fighting white blood cell count. While research to support many of its supposed health benefits is limited, some evidence suggests that cat’s claw … There was a significant decrease of DNA damage and an increase of DNA repair in both cat’s claw supplement groups compared to the non-supplement group. A vine that is also known as Uña de Gato or vilcacora, Cat’s Claw is used as a traditional cure for a wide array of health concerns in Peru, specifically for arthritis, digestive problems, and asthma. In one study in 45 people with osteoarthritis in the knee, taking 100 mg of cat’s claw extract for 4 weeks resulted in reduced pain during physical activity. Cat’s claw prevents the growth of cancer cells. It’s also been used in South American folk medicine to treat arthritis, intestinal complaints and wounds. It allegedly helps fight a range of ailments, including infections, cancer, arthritis, and Alzheimer’s disease (1). A 2001 in vivo study demonstrated that the bark of cat’s claw (Uncaria tomentosa) prevented the growth of human breast cancer cell line MCF7 by having antimutagenic and antiproliferative effects on the cancer cells. Inflammation can really affect one’s daily life. You can also buy cat’s claw tea. The part used medicinally is the inner bark of the vine or root. Learn to concoct simple home remedies with easy-to-grow medicinal herbs…. In this double-blind study, 24 weeks of treatment with the cat’s claw extract resulted in a reduction of the number of painful joints compared to the placebo. Uncaria guianensis is traditionally used for wound healing. It’s said that he improved dramatically, and after a year, he was cancer-free. Chemotherapy is a common conventional cancer treatment with many negative side effects, including damage to the DNA of healthy cells. The extract was obtained from a specific strain of cat’s claw that contains pentacyclic oxindole alkaloids, which are compounds that appear to be immune system modulators. Foundational Support, Immune Support. Both animal and human studies have demonstrated cat claw’s powerful immune-boosting abilities. Studies show that cat’s claw effectively reduces the growth of cancer and tumor cells, thereby reducing the effect of cancer. It’s been used as traditional medicine by indigenous peoples in the Andes to treat inflammation, rheumatism, gastric ulcers, dysentery and even tumors. The two most common varieties are Uncaria tomentosa and Uncaria guianensis. They choose cat’s claw because it has been shown to strengthen the immune system. Despite many marketing claims, there is insufficient evidence to support using cat’s claw for conditions like cancer, allergies, and AIDS. (16). All rights reserved. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Why is this significant? No side effects were reported. Cat's Claw may help create support for the intestinal and immune systems of the body, and may also creates intestinal support with its ability to cleanse the entire intestinal tract. However, more studies are needed. How? Cat’s claw is generally well-tolerated by users and considered non-toxic. It’s been utilized to deal with digestive problems, arthritis, inflammation, ulcers and also to encourage injury healing. (20). As with osteoarthritis, cat’s claw is thought to reduce inflammation in your body, easing rheumatoid arthritis symptoms as a result (6). (5). 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